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技術(shù)文章

PPM1A Antibody Catalog Number:OM218457

點(diǎn)擊次數(shù):23 發(fā)布時(shí)間:2024/9/12 13:28:18
 

Product Profile

Product Name PPM1A Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

 
WB~~1:100~500:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
PPPM1A
Alternative Names
PPM1A
PPPM1A
Protein phosphatase 1A
Protein phosphatase 2C isoform alpha
Protein phosphatase IA
More 
Molecular Weight(MW) 42448 Da
Function
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling
Tissue Specificity This PPM1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human PPM1A.
Cellular Localization Nucleus.

Database Links

Entrez Gene 5494
Nucleotide Accession NP_066283.1;NP_808820.1

Application

  • Application

    PPM1A Antibody (pS) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PPM1A antibody detected the PPM1A protein (arrow).

Application Notes
WB~~1:100~500:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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