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技術(shù)文章

PPM1A antibody Catalog Number：OM269349

點擊次數(shù)：29 發(fā)布時間：2024/9/12 13:24:05
 

Product Profile

Product Name PPM1A antibody
Antibody Type Primary Antibodies
Product description 
Mouse monoclonal [p6c7] to PPM1APPM1A is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 ａnd JNK MAPK pathways ａnd regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.
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Immunogen 
Recombinant full length protein (Human).

Key Feature

Clonality Monoclonal
Isotype IgG2
Clone Number p6c7
Host Species Mouse
Tested Applications

ELISAWB
 
ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity

HumanMouse
Concentration 1 mg/ml
Purification Protein G

Target Information

Gene Synonyms
EC 3.1.3.16 MGC9201 Mpp alpha Protein phosphatase 1A Protein phosphatase 1A magnesium dependent alpha
Target PPM1A
Cellular Localization Cylasmic
Light Chain Type kappa

Application

  • Application

    Western blot analysis of mouse liver cytosol extract using at a dilution of 1/250. Proteins were visualised using a goat anti-mouse secondary antibody conjugated to HRP ａnd a DAB detection system.

Application Notes
ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:

Additional Information

Form Liquid
Storage Instructions Upon receipt - Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid freeze-thaw cycles.
Storage Buffer Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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