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GluR2 antibody, N-term Catalog Number：OM254738

點(diǎn)擊次數(shù)：26 發(fā)布時(shí)間：2024/9/11 13:53:40
 

Product Profile

Product Name GluR2 antibody, N-term
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to GluR2Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain ａnd are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), ａnd function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human ａnd animal studies suggest that pre-mRNA editing is essential for brain function, ａnd defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip ａnd flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]
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Immunogen 
A synthetic peptide corresponding to a N-terminal region of Human GluR2.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-F
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

Mouse
Predicted Reactivity Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Synonyms
GLUR K2
GRIA2
GLUA2
GLUR2
GLURB
HBGR2
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Target GluR2
Molecular Weight(MW) 99 KDa (note)

Application

  • Application

    IHC-Fr analysis of mouse gut tissue using GRIA2 antibody at 20μg/ml.

Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1x PBS buffer with 0.09% (w/v) sodium azide ａnd 2% sucrose.
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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