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技術文章

GluR2 (phospho Ser880) antibody Catalog Number：OM254729

點擊次數(shù)：24 發(fā)布時間：2024/9/11 13:52:03
 

Product Profile

Product Name GluR2 (phospho Ser880) antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to GluR2 (phospho Ser880)Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, ａnd thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly ａnd enters a transient inactive state, characterized by the presence of bound agonist.
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Immunogen 
Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K) derived from Human Glutamate receptor 2.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB
 
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
GLUR2
GLURB
GluA2
GluR-K2
HBGR2
GRIA2
AMPA-selective glutamate receptor 2
gluR-B
gluR-2
glutamate receptor 2
glutamate receptor
ionotropic
AMPA 2
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Target GluR2 (phospho Ser880)
Molecular Weight(MW) 100 (note)

Application

  • Application

    Western blot analysis of extracts from mouse brain tissue using Glutamate receptor 2 (Precursor) (phospho-Ser880) antibody (Lane 2) ａnd the same antibody preincubated with blocking peptide (Lane1).

Application Notes
Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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