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技術(shù)文章

GluR2 (phospho Ser880) antibody Catalog Number:OM254731

點(diǎn)擊次數(shù):25 發(fā)布時(shí)間:2024/9/11 13:50:03
 

Product Profile

Product Name GluR2 (phospho Ser880) antibody
Antibody Type Primary Antibodies
Product description
Rabbit polyclonal antibody to GluR2 (phospho Ser880)Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
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Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to KLH.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

 
Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity

Rat

Predicted Reactivity chicken, human, mouse, non-human primate and Zebrafish(100%)
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
HBGR2
GluR-K2
GluRK2
GRIA2
GLURB
GluA2
GLUR2
GluR K2
GluR2-subunit (phospho S880)
GluR2-subunit (phospho Ser880)
GluR2-subunit (pS880)
GluR2-subunit (pSer880)
GluR2-subunit phospho S880
GluR2-subunit phospho Ser880
Phospho GluR2-subunit (S880
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Target GluR2 (phospho Ser880)
Molecular Weight(MW) 100 (note)
Cellular Localization Interaction with CACNG2 promotes cell surface expression.

Application

  • Application

     

  • Application

    Western Blot: Glutamate receptor 2 [Phospho-Ser880] Antibody [ - rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).

Application Notes
Optimal working dilutions should be determined experimentally by the end user.:

Additional Information

Form Liquid
Storage Instructions For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Storage Buffer 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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