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技術(shù)文章

Product Profile Product NameGRIA2 Antibody TypePrimary Antibodies Immunogen Purified recombinant

點(diǎn)擊次數(shù)：16 發(fā)布時(shí)間：2024/9/11 13:40:50
 

Product Profile

Product Name Glutamate receptor 2 (Precursor) (phospho Ser880) Antibody
Antibody Type Primary Antibodies
Product description 
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, ａnd thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly ａnd enters a transient inactive state, characterized by the presence of bound agonist.1) Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34 (1): 53-67
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Immunogen 
Glutamate receptor 2 (Precursor) (phospho-Ser880) antibody was raised against a peptide sequence around phosphorylation site of serine 880 (I-E-S (p) -V-K) derived from Human Glutamate receptor 2.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB
 
Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol GRIA2
Alternative Names
GLUR2
GLURB
GluA2
HBGR2
GluR-K2
PI12
GRIA2
GluR-2
GluR-B
AMPA 2
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Molecular Weight(MW) 100 kDa
Tissue Specificity This antibody detects endogenous level of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880.

Database Links

Entrez Gene 2891
Protein Accession NP_000817.2

Application

  • Application

    Western blot analysis of lysed extracts from mouse brain tissue using Glutamate receptor 2 (Precursor) (phospho-Ser880).

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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