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技術(shù)文章

ARHGDIA Antibody (N-term) Catalog Number:OM226834

點擊次數(shù):35 發(fā)布時間:2024/9/10 11:26:46
 

Product Profile

Product Name ARHGDIA Antibody (N-term)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

 
WB~~1:100~500:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
GDIA1
Alternative Names
ARHGDIA
GDIA1
Rho GDP-dissociation inhibitor 1
Rho-GDI alpha
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Molecular Weight(MW) 23207 Da
Function
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity)
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Tissue Specificity This ARHGDIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32~61 amino acids from the N-terminal region of human ARHGDIA.
Cellular Localization Cylasm.

Database Links

Entrez Gene 396

Application

  • Application

    Western blot analysis of ARHGDIA Antibody (N-term) in A2058, Jurkat, Ramos cell line and mouse lung tissue lysates (35ug/lane). ARHGDIA (arrow) was detected using the purified Pab.

  • Application

    Western blot analysis of ARHGDIA (arrow) using rabbit polyclonal ARHGDIA Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ARHGDIA gene.

Application Notes
WB~~1:100~500:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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