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聯(lián)系人：楊燕燕

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技術(shù)文章

Annexin A1 Antibody Catalog Number：OM271145

點(diǎn)擊次數(shù)：22 發(fā)布時(shí)間：2024/9/9 13:24:00
 

Product Profile

Product Name Annexin A1 Antibody
Antibody Type Primary Antibodies
Product description 
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 ａnd are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins ａnd leukotrienes, annexin I may have potential anti-inflammatory activity.1) Shimoji,T., J. Cell. Biochem. 106 (6), 1123-1135 (2009)
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Immunogen 
This Annexin A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the Central region of human Annexin A1.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

FACSIHC-PWB
 
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml

Target Information

Gene Symbol ANXA1
Alternative Names
Annexin A1
Annexin I
Annexin-1
Calpactin II
Calpactin-2
Chromobindin-9
Lipocortin I
Phospholipase A2 inhibitory protein
p35
ANXA1
ANX1
LPC1
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Molecular Weight(MW) 39 kDa

Database Links

Entrez Gene 301
Protein Accession P04083

Application

  • Application

    Flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • Application

    Western blot analysis of Annexin A1 antibody in A2058 cell line lysates (35ug/lane)

  • Application

    Annexin A1 Antibody IHC analysis in formalin fixed ａnd paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody ａnd DAB staining.

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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