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技術(shù)文章

CD55 Antibody Catalog Number:OM229250

點(diǎn)擊次數(shù):22 發(fā)布時(shí)間:2024/9/5 13:56:04
 

Product Profile

Product Name CD55 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 561CT4.2.3
Host Species Mouse
Tested Applications

WB

 
WB~~1:100:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
CR
DAF
Alternative Names
CD55
CR
DAF
Complement decay-accelerating factor
CD_antigen=CD55
Flags: Precursor
More 
Molecular Weight(MW) 41400 Da
Function
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade
More 
Tissue Specificity Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix
Cellular Localization Isoform 1: Cell membrane; Single-pass type I membrane protein

Database Links

Entrez Gene 1604
Nucleotide Accession NP_001108224.1

Application

  • Application

    CD55 Antibody(Cat. #AM2092b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CD55 antibody detected the CD55 protein (arrow).

Application Notes
WB~~1:100:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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