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技術(shù)文章

CD59 antibody Catalog Number：OM245691

點(diǎn)擊次數(shù)：33 發(fā)布時間：2024/9/4 15:05:45
 

Product Profile

Product Name CD59 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal antibody to CD59This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, ａnd it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia ａnd thrombosis, ａnd which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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Immunogen 
Recombinant protein of human CD59

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
MIN1
1F5
EL32
MIRL
MAC-IP
HRF-20
G344
EJ30
MIC11
MIN3
MEM43
EJ16
MACIF
MSK21
MIN2
p18-20
CD59 molecule
complement regulatory protein
16.3A5
HRF20
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Target CD59
Molecular Weight(MW) 19 kDa (note)

Application

  • Application

    WB analysis of HeLa lysate using CD59 antibody.

Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.:

Additional Information

Form Liquid
Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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