企業(yè)檔案
- 會員類型：免費會員
- 工商認證： 【已認證】
- 最后認證時間：
- 法人：
- 注冊號：
- 企業(yè)類型：生產(chǎn)商
- 注冊資金：人民幣萬
聯(lián)系我們
聯(lián)系人：楊燕燕
熱門標簽
技術文章
SLC27A5 Antibody (Center) Catalog Number：OM221276
點擊次數(shù)：28 發(fā)布時間：2024/9/3 15:16:29
Product Profile
| Product Name | SLC27A5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
Target Information
| Gene Synonyms | More |
|---|---|
| Alternative Names | More |
| Molecular Weight(MW) | 75385 Da |
| Function | Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine ａnd taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol More |
| Tissue Specificity | Predominantly expressed in liver. |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
Database Links
| Entrez Gene | 10998 |
|---|
Application
-
Application
Western blot analysis of SLC27A5 Antibody (Center) in Hela cell line lysates (35ug/lane). SLC27A5 (arrow) was detected using the purified Pab.
-
Application
Formalin-fixed ａnd paraffin-embedded human kidney reacted with SLC27A5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
-
Application
SLC27A5 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
| Application Notes | WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50: |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
