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技術文章

PDE1B antibody Catalog Number：OM267836

點擊次數(shù)：28 發(fā)布時間：2024/9/3 14:24:43
 

Product Profile

Product Name PDE1B antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to PDE1BThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, ａnd PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP ａnd cGMP, with a preference for cGMP as a substrate. cAMP ａnd cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
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Immunogen 
Recombinant protein of human PDE1B

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ICC/IFIHC-PWB
 
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
PDE1B1
phosphodiesterase 1B
calmodulin-dependent
PDES1B
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Target PDE1B
Molecular Weight(MW) 61 kDa (note)

Application

  • Application

    WB analysis of extracts from various cells using PDE1B antibody.

  • Application

    IHC-P analysis of human kidney cancer using PDE1B antibody at a dilution of 1:200.

  • Application

    IHC-P analysis of human lung cancer using PDE1B antibody at a dilution of 1:200.

  • Application

    ICC/IF analysis of MCF7 cells using PDE1B antibody (green) ａnd DAPI (blue).

  • Application

    ICC/IF analysis of U2OS cells using PDE1B antibody (green) ａnd DAPI (blue).

Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:

Additional Information

Form Liquid
Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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