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技術(shù)文章

PDE1B antibody Catalog Number：OM267838

點(diǎn)擊次數(shù)：28 發(fā)布時(shí)間：2024/9/3 14:21:00
 

Product Profile

Product Name PDE1B antibody
Antibody Type Primary Antibodies
Product description 
Mouse Monoclonal Antibody [10B10B12] to PDE1BThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, ａnd PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP ａnd cGMP, with a preference for cGMP as a substrate. cAMP ａnd cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
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Immunogen 
The immunogen corresponding to a region within amino acids 370 ａnd 536 of human PDE1B expressed in E. Coli.

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 10B10B12
Host Species Mouse
Tested Applications

ELISAFACSWB
 
ELISA: 1/10000.:
Species Reactivity

HumanMouseMonkey
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification  

Target Information

Gene Synonyms
PDE1B1
PDES1B
Target PDE1B
Molecular Weight(MW) 61.4 kDa (note)

Application

  • Application

    ELISA analysis of control antigen ａnd antigen using PDE1B antibody [10B10B12].

  • Application

    FACS analysis of A549 cells using PDE1B antibody [10B10B12] (green) or a negative control (red).

  • Application

    WB analysis of (1) A549, (2) SK-MES-1, (3) mouse brain, (4) PC-12 ａnd (5) 3T3L1 lysates using PDE1B antibody [10B10B12].

  • Application

    WB analysis of lysates from (1) untransfected ａnd (2) PDE1B (a.a. 370-536)-hIgGFc transfected HEK293 cells using PDE1B antibody [10B10B12].

  • Application

    WB analysis of human PDE1B recombinant protein using PDE1B antibody [10B10B12].

Application Notes
ELISA: 1/10000.:

Additional Information

Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Purified antibody in PBS with 0.05% sodium azide ａnd 0.5% protein stabilizer.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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