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Guanylyl Cyclase alpha 1 Antibody Catalog Number：OM280530

點擊次數(shù)：36 發(fā)布時間：2024/9/2 15:09:28
 

Product Profile

Product Name Guanylyl Cyclase alpha 1 Antibody
Antibody Type Primary Antibodies
Product description 
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha ａnd a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP ａnd functions as the main receptor for nitric oxide ａnd nitrovasodilator drugs.1) Saino, M., et al., Oncol. Rep. 12(1):47-52 (2004).
Immunogen 
This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3).

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB
 
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity

Human
Concentration 1 mg/ml

Target Information

Gene Symbol GUCY1A3
Alternative Names
Guanylate cyclase soluble subunit alpha-3
GCS-alpha-3
GCS-alpha-1
Soluble guanylate cyclase large subunit
GUCY1A3
GUC1A3
GUCSA3
GUCY1A1
More 
Molecular Weight(MW) 77 kDa

Database Links

Entrez Gene 2982
Protein Accession Q02108

Application

  • Application

    Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane).

  • Application

    Formalin-fixed ａnd paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

  • Application

    Western blot analysis of GUCY1A3 using GUCY1A3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2).

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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