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聯(lián)系人：楊燕燕
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技術(shù)文章
Anti-WHSC2 antibody Catalog Number：OM642659
點(diǎn)擊次數(shù)：24 發(fā)布時(shí)間：2024/9/2 13:57:45
Product Profile
| Product Name | Anti-WHSC2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:2000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | NELFA |
|---|---|
| Gene Synonyms | |
| Gene Full Name | negative elongation factor complex member A |
| Gene Summary | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, ａnd may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted ａnd tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008] More |
| Molecular Weight(MW) | 57KD |
| Cellular Localization | Nucleus |
Application
-
WB
Western blot analysis using WHSC2 antibody against A549(1) cell lysate.
-
IHC
Immunohistochemical analysis of paraffin-em
bedded bladder cancer tissues using WHSC2 antibody with DAB staining. -
IHC
Immunohistochemical analysis of paraffin-em
bedded esophageal cancer tissues using WHSC2 antibody with DAB staining.
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:2000 |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
