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技術(shù)文章

ITGB4 (phospho Tyr1510) Antibody Catalog Number:OM282419

點擊次數(shù):31 發(fā)布時間:2024/8/29 15:07:20
  

Product Profile

Product Name ITGB4 (phospho Tyr1510) Antibody
Antibody Type Primary Antibodies
Product description
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.1) Suzuki S., EMBO J. 9:757-763(1990).
Immunogen
ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p)-S-T) derived from Human ITGB4 .

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC

 
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity

MouseRat

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol ITGB4
Alternative Names
GP150
ITB4
CD104 antigen
Molecular Weight(MW) 202 kDa
Tissue Specificity The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.

Database Links

Entrez Gene 3691
Protein Accession NP_000204.3

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).

Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

原創(chuàng)作者:上海篤瑪生物科技有限公司

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