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聯(lián)系人：楊燕燕
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技術(shù)文章
CD33 Antibody Catalog Number：OM229206
點擊次數(shù)：34 發(fā)布時間：2024/8/29 15:06:03
Product Profile
| Product Name | CD33 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2B7C12 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB~~1:500 - 2000.: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
Target Information
| Gene Synonyms | |
|---|---|
| Alternative Names | |
| Molecular Weight(MW) | 39825 Da |
| Function | Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cylasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) More |
| Tissue Specificity | Monocytic/myeloid lineage cells. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
Database Links
| Entrez Gene | 945 |
|---|---|
| Nucleotide Accession | NP_001763.3 |
Application
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Application
Figure 1: Western blot analysis using anti-CD33 monoclonal antibody against truncated Trx-CD33 recombinant protein(1),truncated CD33(aa48-258)-His recombinant protein(2) ａnd truncated CD33(aa18-259)-hIgGFc transfected CHO-K1 cell lysate(3).
| Application Notes | WB~~1:500 - 2000.: |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of CD33(48-258) expressed in E. Coli. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
