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FGF4 antibody Catalog Number：OM252983

點(diǎn)擊次數(shù)：18 發(fā)布時(shí)間：2024/8/27 11:52:03
 

Product Profile

Product Name FGF4 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal antibody to FGF4Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic ａnd cell survival activities ａnd play key roles in growth ａnd survival of stem cells during embryogenesis, tissue regeneration, ａnd carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity ａnd is a potent angiogenic factor, expressed in several highly vascularized tumors ａnd also in adult mouse testis, intestine, ａnd brain. Studies on the mouse homolog suggests a function in bone morphogenesis ａnd limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation ａnd neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells ａnd a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
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Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAICC/IFWB
 
ICC/IF:1:200~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

HumanMouse
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
Fibroblast growth factor 4
HBGF-4
FGF4
Heparin secretorytransforming protein
Fibroblast growth factor4
HST1
HST
Transforming protein KS3
HBGF4
Kaposi sarcoma oncogene
HST-1
Heparin secretory-transforming protein
HST 1
HBGF 4
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Target FGF4
Tissue Specificity This antibody is specific for FGF4

Application

  • Application

    Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.

  • Application

    Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 ａnd (B) 1 ug/ml.

  • Application

    Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/ml.

Positive Control Blocking Peptide: Cat.No. GTX85040-PEP - FGF4 Peptide Lysates: Cat. No. GTX27901 - 3T3 (NIH) Cell Lysate
Application Notes
ICC/IF:1:200~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Antibody is supplied in PBS containing 0.02% sodium azide

原創(chuàng)作者：上海篤瑪生物科技有限公司

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