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PI3 kinase p85 alpha antibody Catalog Number：OM268484

點擊次數(shù)：20 發(fā)布時間：2024/8/22 12:01:08
 

Product Profile

Product Name PI3 kinase p85 alpha antibody
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal to PI3 kinase p85 alphaBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake ａnd glycogen synthesis in insulin-sensitive tissues.
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Immunogen 
KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y580 of human PIK3R1.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWB
 
ELISA: Use at 1:1,000:
Species Reactivity

Human
Concentration 0.2 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
Phosphatidylinositol 3-kinase regulatory subunit alpha
PtdIns-3-kinase p85-alpha
PIK3R1
GRB1
Phosphatidylinositol3kinase regulatory subunit alpha
PI3-kinase p85-subunit alpha
PI3K
PI3kinase p85subunit alpha
PtdIns3kinase p85alpha
Phosphatidylinosi
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Target PIK3R1
Molecular Weight(MW) 83.598 kDa (note)

Application

  • Application

    Formalin-fixed ａnd paraffin-embedded human skeletal muscle tissue reacted with PIK3R1-pY580 , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • Application

    Western blot analysis of PIK3R1 (arrow) using rabbit polyclonal PIK3R1 Antibody (Y580) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R1 gene (Lane 2).

Application Notes
ELISA: Use at 1:1,000:

Additional Information

Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot ａnd store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide

原創(chuàng)作者：上海篤瑪生物科技有限公司

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