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技術(shù)文章

PI3K P85 alpha/ gamma/ beta antibody Catalog Number：OM268500

點擊次數(shù)：28 發(fā)布時間：2024/8/21 14:03:01
  

Product Profile

Product Name PI3K P85 alpha/ gamma/ beta antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to PI3K P85 alpha/ gamma/ betaPI3K binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake ａnd glycogen synthesis in insulin-sensitive tissues.
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Immunogen 
Peptide sequence around aa.465~469/197~201/462~466 (L-Y-E-E-Y) derived from Human PI3K P85.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHC-P
 
Suggested starting dilutions are as follows. IHC-P: 1:50~1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
GRB1
p85
p85-ALPHA
PIK3R1
phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
phosphatidylinositol 3-kinase
regulatory subunit
polypeptide 1 (p85 alpha)
PI3K regulatory subunit alpha
ptdIns-3-kinase regulatory subunit alpha
phosphatidyl
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Target PI3K P85 alpha/ gamma/ beta
Molecular Weight(MW) 85 (note)

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PI3K P85 a/g/b(Ab-467/199/464) Antibody (left) or the same anitbody preincubated with blocking peptide

Application Notes
Suggested starting dilutions are as follows. IHC-P: 1:50~1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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