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聯(lián)系人：楊燕燕
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技術(shù)文章
NFE2L2-Y576 Antibody Catalog Number：OM215278
點(diǎn)擊次數(shù)：50 發(fā)布時(shí)間：2024/8/19 14:13:47
Product Profile
| Product Name | NFE2L2-Y576 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
Target Information
| Gene Synonyms | |
|---|---|
| Alternative Names | Hide |
| Molecular Weight(MW) | 67827 Da |
| Function | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region Hide |
| Tissue Specificity | Widely expressed. Highest expression in adult muscle, kidney, lung, liver ａnd in fetal muscle |
| Cellular Localization | Cylasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents |
Database Links
| Entrez Gene | 4780 |
|---|---|
| Nucleotide Accession | NP_006155 |
Application
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Application
Western blot analysis of Phospho-NFE2L2-Y576 in Jurkat cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.
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Application
Formalin-fixed ａnd paraffin-embedded human lung carcinoma reacted with NFE2L2-Y576 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Application
NFE2L2-Y576 Antibody flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell ( histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
| Application Notes | WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50: |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
