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技術(shù)文章

Nrf2 Antibody Phospho (pS40) Catalog Number：OM215668

點(diǎn)擊次數(shù)：11 發(fā)布時(shí)間：2024/8/19 13:47:54
 

Product Profile

Product Name Nrf2 Antibody Phospho (pS40)
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype Cocktail
Clone Number EP1809Y
Host Species Rabbit
Tested Applications

IHCWB
 
WB~~1:1000~10000 IHC~~1:100~250:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
NRF2
Alternative Names
NFE2L2
NRF2
Nuclear factor erythroid 2-related factor 2
Nuclear factor
erythroid derived 2
like 2
HEBP1
More 
Molecular Weight(MW) 67827 Da
Function
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region
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Tissue Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver ａnd in fetal muscle
Cellular Localization Cylasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents

Database Links

Entrez Gene 4780

Application

  • Application

    A. Western blot analysis on A) untreated ａnd B) AP treated HepG2 cell lysates using anti-Phospho-Nrf2 (pS40) RabMAb 1:20,00 dilution.

  • Application

    B. Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-NRF2 RabMAb

Application Notes
WB~~1:1000~10000 IHC~~1:100~250:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide ａnd 0.05% BSA.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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