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聯(lián)系人：楊燕燕
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技術(shù)文章
Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region Catalog Number：OM105377
點擊次數(shù)：25 發(fā)布時間：2024/8/16 11:37:13
Product Profile
| Product Name | Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFWB |
| IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | BovineDogGoatHorseHumanMousePigRabbitRat |
| Concentration | 1 mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | PPARGC1A |
|---|---|
| Gene Synonyms | Hide |
| Gene Full Name | Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| Gene Summary | PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity.The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Hide |
| Alternative Names | Hide |
| Molecular Weight(MW) | 91kDa |
| Sequence | 798 amino acids |
Database Links
| Entrez Gene | 10891 |
|---|---|
| SwissProt ID | Q9UBK2 |
| Protein Accession | NP_037393 |
Application
-
Immunofluorescence
Mouse retina
Primary Antibody Dilution :
1:200
Secondary Antibody :
Donkey anti rabbit-Cy3
Secondary Antibody Dilution :
1:1000
Color/Signal Descriptions :
Red: PPARGC1A
Gene Name :
PPARGC1A
Submitted by :
Dr. Joshua Sanes -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
| Application Notes | IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot ａnd store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
原創(chuàng)作者：上海篤瑪生物科技有限公司
