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PGC1 alpha antibody Catalog Number：OM268254

點擊次數(shù)：24 發(fā)布時間：2024/8/16 11:35:49
 

Product Profile

Product Name PGC1 alpha antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to PGC1 alphaThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity. [provided by RefSeq, Jul 2008]
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Immunogen 
PPARGC1A antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PPARGC1A.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFIHC-PWB
 
WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml:
Species Reactivity

HumanMouse
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
PGC1A
PPARGC1A
PPARGC1
PGC-1(alpha)
PGC-1v
PGC1
LEM6
peroxisome proliferator-activated receptor gamma
coactivator 1 alpha
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Target PGC1 alpha
Tissue Specificity PPARGC1A antibody is human ａnd mouse reactive. At least three isoforms of PPARGC1A are known to exist; this antibody only detects the longest isoform.

Application

  • Application

    Western blot analysis of PPARGC1A in mouse liver tissue lysate with PPARGC1A antibody at (A) 1 ａnd (B) 2 ug/ml.

  • Application

    Immunohistochemistry of PPARGC1A in human liver tissue with PPARGC1A antibody at 5 ug/mL.

  • Application

    Immunofluorescence of PPARGC1A in human liver tissue with PPARGC1A antibody at 20 ug/mL.

Application Notes
WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml:

Additional Information

Form Liquid
Storage Instructions Be stored at 4oC for three months ａnd -20oC, stable for up to one year.
Storage Buffer PBS containing 0.02% sodium azide.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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