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GADD153 antibody

點(diǎn)擊次數(shù)：15 發(fā)布時間：2024/8/15 13:33:18
  

Product Profile

Product Name GADD153 antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to GADD153 (DNA-damage-inducible transcript 3)This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP ａnd LAP (liver activator protein), ａnd preventing their DNA binding activity. The protein is implicated in adipogenesis ａnd erythropoiesis, is activated by endoplasmic reticulum stress, ａnd promotes apoptosis. Fusion of this gene ａnd FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq]
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Immunogen 
Full length human GADD153 Recombinant protein.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWBIHC-R
 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

HumanMouse
Predicted Reactivity Rat, Pig, Rhesus Monkey, BovineRat (90%), Pig (95%), Rhesus Monkey (98%), Bovine (92%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
CEBPZ antibody
CHOP antibody
CHOP-10 antibody
CHOP10 antibody
GADD153 antibody
MGC4154 antibody
DDIT3 antibody
DNA damage-inducible transcript 3 protein antibody
growth arrest ａnd DNA damage-inducible protein GADD153 antibody
c/EBP-homologous prot
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Molecular Weight(MW) 19 kDa (note) (6)
Cellular Localization Nucleus

Application

  • Application

    Sample (30 µg of whole cell lysate) A: HeLa (control) B: HeLa treated with tunicamycin (4ug/ml) 12% SDS PAGE diluted at 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Positive Control HeLa treat tunicamycin (4ug/ml)
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

原創(chuàng)作者：上海篤瑪生物科技有限公司

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