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Occludin antibody

點(diǎn)擊次數(shù)：27 發(fā)布時(shí)間：2024/8/14 15:42:46
  

Product Profile

Product Name Occludin antibody
Antibody Type Primary Antibodies
Product description 
Rabbit Polyclonal antibody to OccludinTight junctions act as a semi-permeable barrier to the transport of ions, solutes, ａnd water ａnd are considered to function as a fence that divides apical ａnd basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling ａnd trafficking molecules regulating cell differentiation, proliferation, ａnd polarity ａnd contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways ａnd can associate with multiple kinases ａnd phosphatases such as PI3-kinase ａnd protein phosphatases 1 ａnd 2A. At least two isoforms of OCLN are known to exist.
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Immunogen 
The immunogen corresponding to a region within amino acids 472 ａnd 522 of human OCLN.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
 
This antibody can be used for detection of OCLN by Western blot at 1 μg/mL. It can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
Occludin
OCLN
Target Occludin
Molecular Weight(MW) 57 kDa (note)
Tissue Specificity This antibody is specific for OCLN

Application

  • Application

    WB analysis of human liver lysate using OCLN antibody at a concentration of 1 μg/ml.

Positive Control Human Liver Tissue Lysate
Application Notes
This antibody can be used for detection of OCLN by Western blot at 1 μg/mL. It can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Antibody is supplied in PBS containing 0.02% sodium azide
 

原創(chuàng)作者：上海篤瑪生物科技有限公司

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