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Caspase 1 antibody (ready-to-use)

點(diǎn)擊次數(shù)：25 發(fā)布時(shí)間：2024/8/13 11:50:42
  

Product Profile

Product Name Caspase 1 antibody (ready-to-use)
Antibody Type Primary Antibodies
Product description 
Rabbit polyclonal to Caspase 1 predilutedCaspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, ａnd large ａnd small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation ａnd inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large ａnd one small subunit, which associate into a2b2 tetramer to form the active enzyme. Caspase 1 is similar to the cell death gene CED3 of C. elegans ａnd regulates multiple proinflammatory cytokines, including Interleukin 1b ａnd interferon-gamma-inducing factor. Caspase 1 plays a role in down stream of Caspase 8 which is involved in Fas-mediated apoptosis.
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Immunogen 
Synthetic peptide (Human, Internal sequence-second quarter of human Caspase 1 protein).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHCIHC-P
 
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
147678
IL1BC
ICE
P29466
P45
Caspase1
Caspase 1
834
CASP1
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Target Caspase 1

Application

  • Application

    Human Placenta stained with anti-Caspase-1 antibody

  • Application

    staining Caspase 1 in human placenta by Immunohistochemistry (FFPE-sections).

  • Application

     

Positive Control Jurkat cells, placenta
Application Notes
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Optimal dilutions/concentrations should be determined by the end user.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution ａnd store at 4°C. Do not freeze.
Storage Buffer PBS, pH 7.4 containing 1%BSA ａnd 0.1% sodium azide

原創(chuàng)作者：上海篤瑪生物科技有限公司

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