Product Identification
【Product Name】p-Hydroxybenzoate ethyl ester 尼泊金乙酯
【Synonyms】Easeptol
【CAS】120-47-8
【Formula】C9H10O3
【Molecular Weight】166.18
【EINECS】204-399-4
【RTECS】DH2190000
【RTECS Class】Drug; Mutagen; Reproductive Effector
【Merck】13,3869
【Beilstein/Gmelin】1101972
【Beilstein Reference】4-10-00-00367

Physical ａnd Chemical Properties
【Appearance】White powder.
【Solubility in water】0.7 g/L
【Melting Point】116 - 118
【Boiling Point】297
【Vapor Pressure】0.00076 (25 C)
【Density】1.078 g/cm3 (131 C)
【pKa/pKb】8.30 (pKb)
【Partition Coefficient】2.47
【Heat Of Vaporization】55.9 kJ/mol
【Heat Of Combustion】-4368 kJ/mol
【Usage】Preservative for pharmaceuticals.

First Aid Measures
【Ingestion】If victim is conscious ａnd alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap ａnd water for at least 15 minutes while removing contaminated clothing ａnd shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper ａnd lower eyelids. Get medical aid immediately.

Handling ａnd Storage
【Storage】Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing ａnd wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, ａnd clothing. Keep container tightly closed. Avoid ingestion ａnd inhalation.

Hazards Identification
【Inhalation】May cause respiratory tract irritation.
【Skin】May cause skin irritation. May cause reddening of the skin. May cause occasional hypersensitivity usually manifested as dermatitis.
【Eyes】May cause eye irritation.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting ａnd diarrhea.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36

尼泊金乙酯Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA＇s eye ａnd face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149
approved respirator when necessary.
【Exposure Effects】

尼泊金乙酯The toxological properties of this substance have not been fully investigated.
【Poison Class】Fire Fighting Measures
【Flash Point】120
【Autoignition】495
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), ａnd full protective gear. During a fire, irritating ａnd highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

Stability ａnd Reactivity
【Incompatibilities】Bases, strong oxidizing agents.
【Stability】Stable under normal temperatures ａnd pressures.
【Decomposition】Carbon monoxide, carbon dioxide.

尼泊金乙酯Transport Information
【HS Code】2918 29 30