艾美捷DetergentOUT GB-S10去垢劑的特點(diǎn)是研究洗滌劑結(jié)合樹脂，對(duì)大多數(shù)洗滌劑具有高親和力，對(duì)蛋白質(zhì)和肽具有低親和力。洗滌劑DetergentOUT GBS10是在ELISA、IEF、蛋白酶消化蛋白質(zhì)和肽電離（通過質(zhì)譜分析）之去除洗滌劑的理想選擇。

DetergentOUT GBS10去垢劑有四種旋轉(zhuǎn)格式柱尺寸或單獨(dú)作為樹脂提供。柱規(guī)格為：

艾美捷DetergentOUT GBS10去垢劑以小的樣品損失從水性蛋白質(zhì)和肽樣品中去除游離的、未結(jié)合的陰離子、非離子或兩性離子洗滌劑（如SDS、Triton®X-100或CHAPS），以便通過質(zhì)譜法（圖1和2）和其他技術(shù)進(jìn)行下游分析。也可提供96孔旋轉(zhuǎn)板格式，用于處理多達(dá)96個(gè)樣品。

DetergentOUT 研究表明，GBS10柱與DI-QTOF和LC-MS/MS完全兼容（見參考文獻(xiàn)）。DetergentOUT的使用™ GBS10柱顯著增加了檢測(cè)到的肽譜的數(shù)量。此外，洗滌劑DetergentOUT GBS10柱對(duì)洗滌劑具有很高的結(jié)合能力，每毫升沉降樹脂含有6毫克SDS和14毫克Triton®X-100。

艾美捷DetergentOUT GBS10去垢劑參考文獻(xiàn)：

Ito-Kureha, T et al (2020) Nat. Comm. doi.org/10.1038/s41467-020-19975-4

Haddock, E. ａnd Feldmann, F. (2017) Validating the Inactivation Effectiveness of Chemicals on Ebola Virus. Methods Mol Biol. 1628:251

Srivastasva, O.P. et al (2017) Post-Translationally Modified Human Lens Crystallin Fragments Show Aggregation in vitro. Biochemistry ａnd Biophysics Report. http://dx.doi.org/10.1016/j.bbrep.2017.01.011

Chiu, J. et al (2016) Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations.Biotechnol Bioeng. DOI: 10.1002/bit.26237

Haddock, E. et al (2016) Effective Chemical Inactivation of Ebola Virus. Emerg Infect Dis. Vol 22:7.

Min, L. et al (2015) Electrophoresis. DOI: 10.1002/elps.201400579

Valente, K. N. et al (2014) Biotechnol Bioeng. DOI: 10.1002/bit.25515

Hou, S. et al (2013) Methods. 61:269

Hashii, N. et al (2005) Proteomics. 5:4665

Higgins, D. et al (2005) Anitmicrob. Agents Chemother. 49:1127

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